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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A1 All Species: 25.15
Human Site: S353 Identified Species: 34.58
UniProt: P68400 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68400 NP_001886.1 391 45144 S353 V S S A N M M S G I S S V P T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112211 397 46613 S353 V S S A N M M S E M R F Y H V
Dog Lupus familis XP_534375 403 46681 S353 V S S A N M M S G Q F Y F S I
Cat Felis silvestris
Mouse Mus musculus Q60737 391 45143 S353 V S S A N M M S G I S S V P S
Rat Rattus norvegicus P19139 391 45055 S353 V S S A N M M S G I S S V P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 Y326 A M E H P Y F Y P V V K E Q S
Chicken Gallus gallus P21868 391 45172 S353 V S S A S M M S G I S S V P T
Frog Xenopus laevis P28020 392 45169 M353 P V S S A S M M S G I S T V P
Zebra Danio Brachydanio rerio NP_001002164 393 45422 I353 P V S T S S M I T G G V T S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 T312 Y D H V D R L T A R E A M A H
Honey Bee Apis mellifera XP_393260 350 41645 Y321 R E A M E H P Y F Y P I V K D
Nematode Worm Caenorhab. elegans P18334 360 42239 G335 E A H A R A N G T E Q A D G Q
Sea Urchin Strong. purpuratus XP_785475 398 46271 S351 S T S A T N S S S A S S T R K
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 L308 R Y D H Q E R L T A L E A M T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08467 333 39240 T309 Y D H Q D R L T A K E A M A H
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 L315 V D L I D N L L R Y D H Q E R
Red Bread Mold Neurospora crassa Q8TG13 336 39621 M312 R L T A K E A M A H P Y F A P
Conservation
Percent
Protein Identity: 100 N.A. 90.4 97 N.A. 97.4 98.4 N.A. 75.4 97.9 94.9 89 N.A. 75.9 79.5 72.8 78.3
Protein Similarity: 100 N.A. 92.1 97 N.A. 98.7 98.9 N.A. 82.6 98.9 97.1 93.8 N.A. 81.8 86.1 82.3 87.1
P-Site Identity: 100 N.A. 53.3 60 N.A. 93.3 100 N.A. 0 93.3 20 13.3 N.A. 0 6.6 6.6 33.3
P-Site Similarity: 100 N.A. 60 60 N.A. 100 100 N.A. 13.3 100 26.6 20 N.A. 33.3 13.3 20 40
Percent
Protein Identity: N.A. 65.2 N.A. 63.4 49.8 61.1
Protein Similarity: N.A. 74.9 N.A. 75.4 63.6 72.8
P-Site Identity: N.A. 6.6 N.A. 0 6.6 6.6
P-Site Similarity: N.A. 6.6 N.A. 33.3 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 6 53 6 6 6 0 18 12 0 18 6 18 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 18 6 0 18 0 0 0 0 0 6 0 6 0 6 % D
% Glu: 6 6 6 0 6 12 0 0 6 6 12 6 6 6 0 % E
% Phe: 0 0 0 0 0 0 6 0 6 0 6 6 12 0 0 % F
% Gly: 0 0 0 0 0 0 0 6 30 12 6 0 0 6 0 % G
% His: 0 0 18 12 0 6 0 0 0 6 0 6 0 6 12 % H
% Ile: 0 0 0 6 0 0 0 6 0 24 6 6 0 0 6 % I
% Lys: 0 0 0 0 6 0 0 0 0 6 0 6 0 6 6 % K
% Leu: 0 6 6 0 0 0 18 12 0 0 6 0 0 0 6 % L
% Met: 0 6 0 6 0 36 48 12 0 6 0 0 12 6 0 % M
% Asn: 0 0 0 0 30 12 6 0 0 0 0 0 0 0 0 % N
% Pro: 12 0 0 0 6 0 6 0 6 0 12 0 0 24 12 % P
% Gln: 0 0 0 6 6 0 0 0 0 6 6 0 6 6 6 % Q
% Arg: 18 0 0 0 6 12 6 0 6 6 6 0 0 6 6 % R
% Ser: 6 36 53 6 12 12 6 42 12 0 30 36 0 12 12 % S
% Thr: 0 6 6 6 6 0 0 12 18 0 0 0 18 0 24 % T
% Val: 42 12 0 6 0 0 0 0 0 6 6 6 30 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 6 0 0 0 6 0 12 0 12 0 12 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _